A question of pain with Dr. Russo

About

A/Prof Marc Russo

Specialist Pain Medicine Physician

MBBS DA FANZCA FFPMANZCA Director, Hunter Pain Specialists, Hamilton Day Surgery, Innervate PMP, Genesis Research Services President, International Neuromodulation Society Conjoint Associate Professor, University of Newcastle Honorary Associate Professor, Dept Anaesthesiology, University of Hong Kong Society Executive Advising Editor, Pain Medicine Deputy Section Editor, Pain Practice Newcastle, NSW, Australia

I am a Specialist Pain Medicine Physician and have treated over 20,000 patients since establishing Hunter Pain Clinic (now Hunter Pain Specialists), Australia's first multidisciplinary private pain clinic, in 1999.

During my clinical career I have conducted a number of world-first treatments, like the spinal cord stimulator implants, as well as first-in-man pain and device studies.

I am the Director of Hunter Pain Specialists, as well as Director of Hamilton Day Surgery and Genesis Research Services, and Co-Director of Innervate Pain Management Services. I was Co-Founder of the Newcastle Anaesthetic Peri-operative Service group.

I am also the founding president of the Neuromodulation Society of Australia and New Zealand (NSANZ), and former Secretary of the International Neuromodulation Society (INS).

In addition, I serve on the Examination Committee, the Professional Standards Committee, the Research and Innovation Committee, and the Procedures Working Group for the Faculty of Pain Medicine (ANZCA).

I'm a Conjoint Lecturer at the University of Newcastle, NSW, Australia, and an Associate Professor at the University of Hong Kong.

My passion is furthering the boundaries of pain medicine and teaching colleagues in state-of-the-art pain management, contributing to the collective knowledge of my peers. With this in mind, I have published over 40 papers in the field of pain medicine and is a reviewer for the National Health and Medical Research Council (NHMRC), as well as a number of international journals.

Work

Research Experience

2020

Study ID TLC599A3005 A Phase 3, Randomized, Double-blind, Placebo- and Active controlled Study to Evaluate the Efficacy and Safety of TLC599 in Patients with Osteoarthritis of the Knee

Phase: III Sponsor: Taiwan Liposome Company CRO: Premier Research Ongoing

2019

Study ID TOU-CIP-01 A Data Acquisition Study for the Tournicare Blood Pressure Monitor

Phase: Pre-Market Sponsor: Tournicare CRO: Mobius Medical Ongoing

Study ID GRS2018-006 A Prospective, Multicentre Study of Low Dose Targeted Drug Delivery (TDD) for Chronic Back Pain Patients who have Failed Spinal Cord Stimulation.

Phase: Open-Label Sponsor: Genesis Research Services CRO: Mobius Medical Ongoing

Study ID PMH-001 Single-Arm, Multicenter, Study to Evaluate Safety and Efficacy of Low Frequency

Spinal Cord Stimulator in Subjects with Low Back and/or Leg Pain.

Phase: First-in-Human Sponsor: Presidio Medical CRO: Five Corners Ongoing

Study ID CA2019-01 OUS DENALI A Multi-Center, Prospective Clinical Trial of Spinal Cord Stimulation with Varying Parameters for the Treatment of Chronic Back and/or Leg Pain.

Phase: N/A Sponsor: Nevro CRO: Five Corners Ongoing

Study ID ILS-CIP-002 Buffered GEnipin Microinvasive Device for Treatment of Low Back Pain from Degenerative Disc Disease - CE Marking Safety and Efficacy Study (GEM-SE).

Phase: II Sponsor: Intralink-Spine CRO: Five Corners Ongoing

Study ID CLIN-0012-STA01-19 A Double-Blind, Randomized, Placebo-Controlled Parallel-Group Study to Assess the Safety and Efficacy of Two Doses of SX600 Administered by Lumbosacral Transforaminal Epidural Injection in Patients with Radicular Pain Secondary to Lumbar Intervertebral Disc Herniation (SALIENT).

Phase: I/II Sponsor: SpineThera CRO: Neuroscience Trials Australia Ongoing

Study ID FLU009 A Phase 2b Study to Determine the Efficacy of Candidate Influenza Vaccine MVA-NP+M1 in Adults aged 18 years and over.

Phase: 2b Sponsor: Vaccitech CRO: Clinical Network Services Ongoing

Study ID GRS2017-001 A Prospective, Single-Blinded, Dose-Response Study of SCS Therapy using Subthreshold Waveform Patterns in Patients with Chronic Neuropathic Low Back Pain.

Phase: Open-Label Sponsor: Genesis Research Services CRO: Five Corners Ongoing

CURRICULUM VITAE Dr Marc A Russo (MBBS DA (UK) FANZCA, FFPMFANZCA)

Academic CV – 9 February 2021 Dr Marc Russo Academic CV.docx 14

Study ID A7007 A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain (RELIEF-2).

Phase: Global Registry Study Sponsor: Boston Scientific

2018

Study ID USYD CRPS PDN Immune profiling of peripheral blood mononuclear cells from patients with Complex Regional Pain Syndrome and Diabetic Peripheral Neuropathic Pain using mass cytometry.

Phase: Pilot Sponsor: Genesis Research Services Ongoing

Study ID CEMA401A2202 A double-blind, placebo-controlled, randomized trial to determine the safety and efficacy of EMA401 100 mg b.i.d. in reducing 24-hour average pain intensity score in patients with painful diabetic neuropathy (EMPADINE).

Phase: II Sponsor & CRO: Novartis

Study ID LDS-102 A Phase II, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of topical Lidocaine Spray in Patients with Postherpetic Neuralgia.

Phase: II Sponsor: Andros Pharmaceuticals CRO: Novotech

2017

Study ID TLC559A2003 A Phase IIa, Randomized, Double-blinded, Placebo-controlled, Dose-finding Study for Single-Dose Administration of TLC599 in Patients with Osteoarthritis (OA) of Knee.

Phase: IIa Sponsor: Taiwan Liposome Company CRO: Novotech

Study ID 950002 ReActiv8 Implantable Neurostimulation System for Chronic Low Back Pain (ReActiv8-B).

Phase: Pre-Market Sponsor: Mainstay Medical CRO: Five Corners Ongoing

Study ID ZYN2-CL-005 A Phase 2A, Randomized, Double-Blind, Placebo-Controlled, Multiple Center, Multiple-Dose Study to Assess the Efficacy and Safety of ZYN002 Administered as a Transdermal Gel to Patients with Knee Pain due to Osteoarthritis.

Phase: IIa Sponsor: Zynerba

Study ID A4091058 A Phase 3 Randomized, Double-blind, Active-controlled, Multicenter Study Of The Long-term Safety And Efficacy Of Subcutaneous Administration Of Tanezumab In Subjects With Osteoarthritis Of The Hip Or Knee.

Phase: III Sponsor: Pfizer

Study ID MT-GPRT-KOA01 A randomised, double-blind using blinded evaluator, placebo and active controlled, pilot study to evaluate the safety and efficacy of intra articular administration of Articul One in patient with symptomatic primary knee osteoarthritis.

CURRICULUM VITAE Dr Marc A Russo (MBBS DA (UK) FANZCA, FFPMFANZCA)

Academic CV – 9 February 2021 Dr Marc Russo Academic CV.docx 15

Phase: II Sponsor: Medytox

2016

Study ID SCLSH1502 Avalon: A study to evaluate the safety and performance of a new Spinal Cord Stimulation System using automatic control to treat patients with chronic pain.

Phase: Pre-Market Sponsor: Saluda Medical CRO: Mobius Medical

Study ID AXS02-K301 COAST-1: Clinical Knee Osteoarthritis Symptom Treatment 1 Study

A Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of AXS-02 (Disodium Zoledronate Tetrahydrate) Administered Orally to Subjects with Knee Osteoarthritis Associated with Bone Marrow Lesions.

Phase: III Sponsor: Axsome Therapeutics

Study ID AXS02-301 CREATE-1: A Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of AXS-02 (Disodium Zoledronate Tetrahydrate) Administered Orally to Subjects with Complex Regional Pain Syndrome Type I (CRPS-I).

Phase: III Sponsor: Axsome Therapeutics

Study ID CA2013 OUS ULN Multi-Centre, Prospective Clinical Trial of the Senza™ Spinal Cord Stimulation (SCS) System in the Treatment of Chronic Upper Limb and Neck Pain.

Phase: Pre-Market Sponsor: Nevro

Study ID FX006-2014-008 A Double-Blind, Randomized, Single-Dose Study to Assess the Safety and Efficacy of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the Knee.

Phase: III Sponsor: Flexion Therapeutics

2015

Study ID POH035-13 A Randomized, Double-Blind, Crossover, Phase IIa Study Comparing a Single-Application TPM®/Oxycodone Patch versus Vehicle Patch in the Topical Treatment of Patients with Postherpetic Neuralgia.

Phase: IIa Sponsor: Phosphagenics

Study ID COR1.1 A Multi centre, Randomized, Double-blind Study to Evaluate the Safety and Efficacy of Hydros and Hydros-TA Joint Therapies for Management of Pain Associated with Osteoarthritis in the Knee.

Phase: III Sponsor: Carbylan Therapeutics

2014

Study ID 950057 Investigation of the ReActiv8® Implantable Stimulation System for Chronic Low Back Pain (ReActiv8-A).

Phase: Pre-Market Sponsor: Mainstay Medical CRO: Five Corners Ongoing

Study ID A7007 A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain (RELIEF).

Phase: Global Registry Study Sponsor: Boston Scientific

Study ID AUX-CC-871 A randomized, double-blind, placebo-controlled study of the safety and efficacy of AA4500 for the treatment of adhesive capsulitis of the shoulder.

Phase: IIb Sponsor: Auxilium Pharmaceuticals CRO: Novotech

Study ID SMCSh10 A feasibility study evaluating the Saluda SCS system incorporating feedback control using Evoked Compound Action Potentials (ECAP) to aid in the accurate positioning of Spinal Cord Stimulation (SCS) leads.

Phase: Pre-Market Sponsor: Saluda Medical

Study ID C-13-03 BURST Pre-Market Clinical Study.

Phase: N/A Sponsor: St Jude Medical

2013

Study ID 2012-03-699 A Multicenter Prospective Observational Study on the Safety and Efficacy of High Frequency Spinal Cord Stimulation in Complex Regional Pain Syndrome Patients.

Phase: Open Label Sponsor: Dr Marc Russo (Nevro)

Study ID SPStim: Whisper2013 An investigation into the therapeutic effect of electrical impulses with short pulse (SP) width on pain relief and quality of the spinal cord stimulation (SCS) in patients with intractable back and / or leg pain.

Phase: Open Label Sponsor: Boston Scientific

Study ID A5004 - OPTIONS Precision Spectra™ Neurostimulator System for the Treatment of Chronic Intractable Pain of the Trunk and/or Limbs.

Phase: Prospective Sponsor: Boston Scientific

Study ID 178-CL-102 A Randomized, Double-Blind, Parallel-Group, Active-Controlled, Multi-center Study to Evaluate the Long-Term Safety and Efficacy of Combination of Solifenacin Succinate with Mirabegron Compared to Solifenacin Succinate and Mirabegron Monotherapy in Subjects with Overactive Bladder

Phase: III Sponsor: Astellas

Study ID 178-CL-101 A Randomized, Double-Blind, Parallel-Group, Placebo- and Active- Controlled, Multi-center Study to Evaluate the Efficacy, Safety and Tolerability of Combinations of Solifenacin Succinate and Mirabegron Compared to Solifenacin Succinate and Mirabegron Monotherapy in the Treatment of Overactive Bladder.

Phase: III Sponsor: Astellas

Study ID 1.02.7007 SubQStim: Interventional, Prospective, Multicenter, Randomized, Parallel-arm Study to Compare the Effectiveness of Peripheral Nerve Stimulation (PNS) Utilizing a Subcutaneous Lead Implant Technique (SQS) Plus Optimized Medical Management (OMM) Versus OMM Alone in Patients Suffering From Back Pain Due to Failed Back Surgery Syndrome (FBSS).

Phase: IV Sponsor: Medtronic

Study ID CI-10-029-ID-SC SCS Heart Study- Spinal Cord Stimulation for heart Failure as a Restorative Treatment.

Phase: I Sponsor: St Jude Medical

Study ID RHGDF-5-02 A Phase I/IIa, Multicenter, Open-label, Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal rhGDF-5 for the Treatment of Early Stage Lumbar Disc Degeneration

Phase: I/IIa Sponsor: DePuy Spine Inc CRO: Janssen-Cilag

Study ID V89_04 and V89_13 A Randomized, Observer-Blind with Single-Blind Booster, Multi Centre, Study to Evaluate Safety, Tolerability and Immunogenicity of an Adjuvanted Cell Culture-Derived H5N1 Subunit Influenza Virus Vaccine at Two Different Formulations in Healthy Adult and Elderly Subjects.

Phase: II Sponsor and CRO: Novartis

2012

Study ID C-09-01 Partnership for Advancement in Neuromodulation (PAIN): A Prospective Clinical Outcomes Registry.

Phase: Observational Sponsor: St Jude Medical

Study ID AUX-CC-867 An Open-label Historically Controlled Study to Assess the Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects with Multiple Dupuytren’s Contractures with Palpable Cords.

Phase: IIIb Sponsor: Auxilium Pharmaceuticals CRO: Novotech

Study ID A7002 Precision High-Rate Sub-perception Spinal Cord Stimulation for the Treatment of Chronic Intractable Pain.

Phase: Prospective Sponsor: Boston Scientific

Study ID OXN3506 A randomised, double-blind, double-dummy, parallel-group multicentre study to demonstrate improvement in symptoms of constipation and noninferiority in analgesic efficacy in subjects with non-malignant or malignant pain that requires around-the-clock opioid therapy taking 50/25 – 80/40 mg twice daily as oxycodone/naloxone prolonged release (OXN PR) tablets compared to subjects taking 50 - 80 mg twice daily oxycodone prolonged release (OxyPR) tablets alone.

Phase: III Sponsor: Mundipharma

Study ID FX006-2011-001 A Double Blind, Randomised, Parallel Group, Dose-Ranging Study Comparing FX006 to Commercially Available Triamcinolone Acetonide Injectable Suspension in Patients with Osteoarthritis of the Knee.

Phase: II Sponsor: Flexion Therapeutics CRO: Novotech

Study ID 02-SMI-2010 A Prospective Trial to Assess the Safety and Performance of the Spinal Modulation Neurostimulator System in the Treatment of Chronic Pain.

Phase: Prospective Sponsor: Spinal Modulation CRO: Five Corners

Study ID TH1124 A Multi-Centre, Randomised, Double-Blinded, Placebo Controlled, Parallel Group, Multiple Dose Study of the Efficacy of 8.75mg Flurbiprofen Spray in the Relief of Sore Throat due to URTI.

Phase: III Sponsor: Reckitt Benckiser CRO: Novotech

Study ID F1J-EW-HGMQ Use of Duloxetine or Pregabalin in Monotherapy versus Combination Therapy of Both Drugs in Patients with Painful Diabetic Neuropathy “The COMBO – DN” (Combination vs Monotherapy of Pregabalin and duloxetine in Diabetic Neuropathy).

Phase: IIIb Sponsor: Eli Lilly CRO: Parexel

2011

Study ID BUP3029 Efficacy and safety of Transdermal Buprenorphine (Norspan BTDS) and placebo in patients with Diabetic Peripheral Neuropathic Pain (DPNP).

Phase: IIIb Sponsor and CRO: Mundipharma

Study ID A3191172 A Randomized, Double Blind, Parallel-Group Study of Cardiovascular Safety in Osteoarthritis or Rheumatoid Arthritis Patients with or At High Risk for Cardiovascular Disease Comparing Celecoxib with Naproxen and Ibuprofen.

Phase: IV Sponsor: Pfizer CRO: Quintiles

Study ID HMX3501 A confirmatory, placebo-controlled, randomised, double-blind, single dummy, parallel group, ratio-finding study in constipated pain patients to establish an optimal Hydromorphone – naloxone ratio with an improved bowel function and a comparable analgesic efficacy compared to Hydromorphone alone.

Phase: II/III Sponsor: Mundipharma CRO: Parexel

2010

Study ID S2-3.3.013 A Randomised, Double-Blinded Study to Assess Safety, Immunogenicity, and Lot Consistency of Solvay’s Cell Derived Influenza Vaccine.

Phase III Sponsor: Solvay Biologicals

Study ID 3200K1-3358-WW Open-label study to evaluate the Long-Term Safety of Subcutaneous MOA-728 for Treatment of Opioid-Induced Constipation in Subjects with Non-malignant Pain.

Phase: III Sponsor: Wyeth

Study ID BUP3026-A1 A Multicentre, Randomised, Double-Blind, Parallel Group Comparison of The Efficacy and Safety of Transdermal Buprenorphine (Norspan® TDS) And Placebo in Participants with Post Herpetic Neuralgia

Phase: III/IV Sponsor: Mundipharma CRO: DataPharm

Study ID H9B-MC-BCDH Dose-Ranging Study of Multiple Subcutaneous Doses of LY2127399, an Anti-BAFF Human Antibody, in Participants with Active Rheumatoid Arthritis despite Ongoing Methotrexate Therapy.

Phase: II Sponsor: Eli Lilly and Company CRO: Omnicare Clinical Research

2009

Study ID TH0819 A multi-multi centre, randomised, double-blind, placebo-controlled, parallel group, multiple dose, study of the efficacy of 8.75mg Flurbiprofen micro granules in the relief of sore throat due to upper respiratory tract infection.

Phase: III Sponsor: Reckitt Benckiser CRO: Novotech2009

Study ID DCF-006 A randomised, double-blind, placebo-controlled study of the efficacy and safety of a diclofenac sodium patch for the topical treatment of acute pain due to mild to moderate soft tissue injuries.

Phase: III Sponsor: Cerimon Pharmaceuticals CRO: Novotech

Study ID MKN106762 A Double-Blind Placebo-Controlled study of the efficacy and safety of the p38 Map kinase inhibitor SB681323 in patients with neuropathic pain following nerve trauma.

Phase: II Sponsor: GlaxoSmithKline

2008

Study ID R331333PAI3011 A Randomised Double-Blind, Placebo-and-Active-Control, Parallel-arm, Phase III Trial with Controlled Adjustment of Dose to Evaluate the Efficacy and Safety of CG5503 Extended –Release (ER) in Subjects with Moderate to Severe Chronic Low Back Pain.

Study ID R331333PAI3008 A Randomised Double-Blind, Placebo-and-Active-Control, Parallel-arm, Phase III Trial with Controlled Adjustment of Dose to Evaluate the Efficacy and Safety of CG5503 Extended –Release (ER) in Subjects with Moderate to Severe Pain Due to Osteoarthritis of the Knee.

Phase: III Sponsor: Janssen-Cilag CRO: Kendle

Study ID A3200479 A Study to Compare Two Contrasting Paracetamol Formulations In The Management of Osteoarthritis Pain.

Sponsor: GlaxoSmithKline CRO: Omnicare Clinical Research

2007

Study ID P-AD337-021 A Multi-Centre, Randomised, Double-Blind, Placebo Controlled, Parallel Group Exploratory Study to Investigate the Efficacy, Safety and Tolerability of AD 337 in the Treatment of Fibromyalgia in Female Subjects.

Phase: II Sponsor: Sosei CRO: Trident Clinical Research

Study ID SB-767905/014 A Randomized, Double-Blind, Placebo- Controlled, Multicentre Phase III Study to Evaluate the Long-Term Safety of Alvimopan 0.5mg Twice Daily for 12 Months for the Treatment of Opioid-Induced Bowel Dysfunction in Adults taking Opioid Therapy for Persistent Non-Cancer Pain.

Phase: III Sponsor & CRO: Cubist Pharmaceuticals, GlaxoSmithKline

2006

Study ID SB-767905/013 A Randomized, Double-Blind, Placebo- Controlled, Multicentre Phase III Study to Evaluate the Efficacy and Safety of Alvimopan 0.5mg Once Daily and 0.5mg Twice Daily for12 weeks for the Treatment of Opioid-Induced Bowel Dysfunction in Adults taking Opioid Therapy for Persistent Non-Cancer Pain.

Phase: III Sponsor & CRO: Cubist Pharmaceuticals, GlaxoSmithKline

Study ID ABD 106239 An Observational Survey to Characterize the Burden of Illness Associated with Laxative Use in Subjects using Opioids for the Management of Persistent Non-Cancer Pain.

Sponsor & CRO: GlaxoSmithKline

Professional Life/Research Interests

Current Appointments

Professional Qualifications and Employment History

Certifications

External Current Appointments

External Past Appointments

Current Professional Memberships

Reviewer of these Journals

Awards

Conferences/Teaching/Professional Development (Last 4 years)

2021

January North American Neuromodulation Society Virtual Meeting

15-16 January

• On-demand presentation: Long Term Results of DRG Stimulation

2020

January North American Neuromodulation Society 22nd Annual Meeting

23-26 January; Las Vegas, NV, USA

May International Neuromodulation Society Webinar

7 May

• Panelist: Neurostimulation Appropriateness Consensus Committee (NACC): Safety Guidelines for the Reduction of Severe Neurological Injury

November PAIN2020 Virtual Conference

14-15 May

• Conference Convenor

• Presentation (plenary session): Medicinal Cannabis – Getting it Right

• Presentation (plenary session): Introducing Radiofrequency Capsulorrhaphy

• Moderator: ReActiv8 Restorative Neurostimulation for Chronic Mechanical Low Back Pain

2019

January North American Neuromodulation Society 21st Annual Meeting

17-20 January; Las Vegas, NV, USA

• Presentation: Neural Response Profile: Objective Neurophysiological Measurements and Pain Relief in Spinal Cord Stimulation.

• Presentation: The Therapy is Failing: Overstimulation, Programming and Device Solutions.

May Webcast for Seqirus (bioCSL)

7 May; NSW, Australia

• Presentation: First Do No Harm - Effective Opioid Use for Improved Patient Outcomes

International Neuromodulation Society 14th World Congress

25-30 May; Sydney, NSW, Australia

• INS Director-at-Large

• Chair (pre conference): Innovations in Neuromodulation

• Presentation (plenary session): Medical Device Monitoring: Where are We and Where do We Need to Go?

July Module 4 APAC (Abbott)

25-29 July; Singapore, Mandarin Oriental

August Stimwave Cadaver Course

11 August; Brisbane, QLD, Australia

Medtronic Medical Advisory Board Meeting

19-21 August; Loews Minneapolis Hotel, Minneapolis, MN, USA

October Faculty of Pain Medicine Spring Meeting

18-20 October; Byron Bay, NSW Australia

Tilray Advisory Board Meeting

30 October; Sydney NSW Australia

November NSANZ Strategic Planning Meeting

29 November; Melbourne VIC Australia

Faculty of Pain Medicine Examinations – Examiner

30 November; Melbourne VIC Australia

December Faculty of Pain Medicine Examinations – Examiner

1 December; Melbourne VIC Australia

Saluda Medical Principal Investigators Meeting

10 December; Gladesville NSW Australia

Faculty of Pain Medicine – Examination Pathways Meeting

15 December; Melbourne VIC Australia

2018

January North American Neuromodulation Society 21st Annual Meeting

11-15 January; Las Vegas, NV, USA

• Presentation: Long-Term Results from the Avalon Study - Closed-Loop SCS using Evoked Compound Action Potentials.

• Presentation co-author: Spinal Cord Stimulation at 10 kHz for Chronic Upper Limb and Neck Pain: Australian Experience.

• Session moderator: Management of Axial Spinal Pain.

April Neuromodulation Society of Australia & New Zealand 13th Annual Scientific Meeting

7-8 April; Sydney, NSW, Australia

• Scientific Convener NSANZ 2018

• Presentation (Medtronic breakfast session): Introducing Intellis with Evolve. Personalised, future-proof chronic pain management.

• Chair (plenary session): Updates from the experts.

• Presentation: Recognising and shutting down A-Beta Nociceptor activation.

• Presentation: How many techniques does one need to master?

May 87th Annual Scientific Congress of the Royal Australasian College of Surgeons in partnership with the American College of Surgeons & ANZCA

7-11 May; Sydney, NSW, Australia

• Cadaver Preceptor: Interventional pain techniques.

• Presentation: Neuromodulation in the virgin spine.

• Presentation: CRPS – What we know and what we don’t know.

June FPM Consultative Forum: Opioids and Chronic Pain – continuing the conversation

16 June; Melbourne, VIC, Australia

• Invited Speaker: Historical context of opioid prescribing.

Workers Compensation Commission Annual Conference

June; Sydney, NSW, Australia

• Lecture: Muscle control and low back pain

Department of Health MBS Review Team Meeting

28 June; Melbourne, VIC, Australia

• Pain Management Representative.

August International Neuromodulation Society Second Interim Meeting

8-11 August; Rio de Janeiro, Brazil

• Presentation: Spinal Cord Stimulation for Complex Regional Syndrome: what are the evidences?

• Presentation: Spinal Cord Stimulation in the virgin spine.

2017

April Australian Pain Society 37th Annual Scientific Meeting: 'Expanding Horizons' 9-12 April; Adelaide, SA, Australia.

• Presentation (Pierre Fabre breakfast session): Fibromyalgia: Perspectives from rheumatology and pain management.

• Presentation (topical session): Neuromodulation: The science, the evidence and the application in multidisciplinary pain management.

• Presentation (Seqirus breakfast session): Real word experience with Tapentadol – The Australian Experience.

May International Neuromodulation Society 13th World Congress

27 May – 1 June; Edinburgh, Scotland, UK

• Chair (preconference): Innovations in Neuromodulation. The Challenge of Reimbursement: Can we do this Smarter?

• Plenary session: Welcome and INS Leadership Message.

• Moderator: Evoked Compound Action Potentials: Mechanism of Action and Clinical Applications in Neuromodulation.

• Presentation: Clinical Evidence and Long Term Results from a Multi‐Center, Prospective Clinical Trial to Evaluate Feedback in Spinal Cord Stimulation for Chronic Back and Leg Pain.

October Faculty of Pain Medicine Procedures in Pain Medicine Forum 2017 20 October; Melbourne, VIC, Australia

• Presentation: What are the current cost and efficacy debates within the field?

2016

February Webinar: Advanced RF Workshop, Sydney Eye Hospital, Sydney, NSW, Australia.

March Neuromodulation Society of Australia & New Zealand 11th Annual Scientific Meeting

12 – 13 March; Perth, WA, Australia

• Presentation: Patient variability and the Dynamic Nature of Pain: Customising Therapy with Multiple Waveform Options.

• Chair: Comparing Neuromodulation to other treatment options.

April 14th Annual Faculty of Pain Medicine Refresher Course Day: “Extremes of Pain” 29 April; Auckland, New Zealand.

Long Case Assessment - Faculty of Pain Medicine (ANZCA)

Royal North Shore Hospital, Sydney, NSW, Australia.

May Lingard Private Hospital Medical Advisory Board Meeting, Mereweather, NSW, Australia.

Nevro Scientific Advisory Board Meeting, San Francisco, CA, USA.

June Peer to Peer Mentoring in Practice Set Up and Management.

CURRICULUM VITAE Dr Marc A Russo (MBBS DA (UK) FANZCA, FFPMFANZCA)

Academic CV – 9 February 2021 Dr Marc Russo Academic CV.docx 10

Presentation on Palexia for Seqirus (bioCSL).

July International Neuromodulation Society Meeting Edinburgh, Scotland, UK.

August Hunter Pain Clinic GP Education Session Presentation at Toowoon Bay, NSW, Australia.

Hunter Postgraduate Medical Institute, Mayfield, NSW, Australia

• Guest panel member: GP Education Day Case Study.

Host visit from Professor Paul Glare, Sydney Medical School, Chair of Pain Medicine, Broadmeadow, NSW, Australia.

Peer to peer mentoring with Dr Timothy Deer from The Center for Pain Relief, USA.

2015

January Medtronic Advisory Committee Meeting.

February Presentation: St Jude Symposium, Melbourne, VIC, Australia.

GP presentation: Use of Medicines in Pain Management (sponsor: bioCSL), Muswellbrook, NSW, Australia.

GP masterclass (sponsor: Mundipharma), Charlestown, NSW, Australia.

March GP presentation: Use of Medicines in Pain Management (sponsor: bioCSL) Wyong, NSW, Australia.

GP presentation: Use of Medicines in Pain Management (sponsor: bioCSL) Newcastle, NSW, Australia.

Presentation / demonstration: Boston Scientific Cadaver Laboratory Brisbane, QLD, Australia.

Australian Pain Society 35th Annual Scientific Meeting: “Managing Pain: From Mechanism to Policy” 15 – 18 March, Brisbane, QLD, Australia

• Presentation (topical session): Interventional management of pain as part of contemporary multidisciplinary care.

CURRICULUM VITAE Dr Marc A Russo (MBBS DA (UK) FANZCA, FFPMFANZCA)

Academic CV – 9 February 2021 Dr Marc Russo Academic CV.docx 11

• Breakfast presentation (bioCSL): Pain intensity vs. functional improvement… time to shift our thinking.

Boston Scientific Scientific Advisory Board, Dallas, TX, USA.

Faulty of Pain Medicine (ANZCA) Appointed lead - Authoring Group for Pain Medicine Optional Topic Area.

April Faculty of Pain Medicine (ANZCA) Refresher Course, Adelaide, SA, Australia Presenter and participant.

May General Practice Conference & Exhibition, Sydney, NSW, Australia

• Presentation: Targeting Multiple Pain Pathways in the Treatment of Chronic Pain.

16th European Federation of National Associations of Orthopaedics and Traumatology Congress, 27 – 29 May; Prague, CZ.

Australian and New Zealand College of Anaesthetists Annual Scientific Meeting

2 – 5 May; Adelaide, SA, Australia

• Presentation: Marijuana – The Debate.

The Hunter Postgraduate Medical Institute - Hamilton Cluster Meeting Mayfield, NSW, Australia

• Presenter: Joint Pain - What can be done?

June International Neuromodulation Society 12th World Congress 6 – 11 June; Montreal, Quebec, Canada

• Presentation: Setting a Global Target: Neuromodulation Accessibility for All Who Need It.

Erina Family Medicine, NSW, Australia

• Presentation: Advances in Pain Medicine.

Gosford Private Hospital, NSW, Australia

• Presentation: Resident Education.

West Lake Medical Association, NSW, Australia

• Presentation: Advances in Pain Medicine.

August Macquarie University Hospital, NSW, Australia.

• Lab demonstration: Spinal Cord Stimulation (Mainstay Medical)

CURRICULUM VITAE Dr Marc A Russo (MBBS DA (UK) FANZCA, FFPMFANZCA)

Academic CV – 9 February 2021 Dr Marc Russo Academic CV.docx 12

September Presentation: PRP for Joint Injections (sponsor: Australasian Medical & Scientific Limited).

75th FIP World Congress of Pharmacy and Pharmaceutical Sciences 29 September - 3 October; Düsseldorf, Germany.

October Faculty of Pain Medicine (ANZCA) Spring Meeting

• Presenter: Challenges and Adventures in Private Practice.

Presentation: An Holistic Approach to Osteoarthritis (sponsor: Mundipharma) Central Coast, NSW, Australia.

Presentation: Norspan and its Uses (sponsor: Mundipharma), Charlestown, NSW, Australia.

November Presentation: Norspan and its Uses (sponsor: Mundipharma), Maitland, NSW, Australia.

Examiner for Faculty of Pain Medicine ANZCA examinations, Melbourne, VIC Australia.

Presentation: Advances in Medications for Pain (sponsor: bioCSL), Central Coast, NSW, Australia.

December North American Neuromodulation Society 19th Annual Meeting 10 – 13 December; Las Vegas, NV, USA

• Presentation (plenary session): Neurostimulation Approaches for Back Pain.

Publications

2021

Persistent Spinal Pain Syndrome: a proposal for Failed Back Surgery Syndrome and ICD-11

Christelis N, Russo M, Stanton-Hicks M, Barolat G, Thomson S, Schug S, Baron R, Buchser E, Carr DB, Deer TR, Dones I, Eldabe S, Gallagher R, Huygen F, Kloth D, Levy R, North R, Perruchoud C, Petersen E, Rigoard P, Slavin K, Turk D, Wetzel T, Loeser J.

Pain Medicine. 2021; Jan 27.

2020

Practice Choices in Targeted Intrathecal Drug Delivery: An Online Survey Conducted by the Polyanalgesic Consensus Committee

Deer TR, Abd-Elsayed A, Falowski S, Hagedorn JM, Abejón D, Russo M, Hah JM, Lamer TJ, Carayannopoulos AG, Hunter C, Steegers M, Pope J.

Neuromodulation. 2020; Dec 23.

Letter to the Editor Re: "A Randomized Double-Blind Controlled Pilot Study Comparing Leucocyte-Rich Platelet-Rich Plasma and Corticosteroid in Caudal Epidural Injection for Complex Chronic Degenerative Spinal Pain" by Ruiz-Lopez and Tsai.

Russo M, Volschenk W, Santarelli DM.

Pain Practice. 2020; Dec 9.

Kynurenine, Tetrahydrobiopterin, and Cytokine Inflammatory Biomarkers in Individuals Affected by Diabetic Neuropathic Pain

Staats Pires A, Heng B, Tan VX, Latini A, Russo M, Santarelli DM, Bailey D, Wynne K, O’Brien JA, Guillemin GJ, Austin PJ

Frontiers in Neuroscience. 2020; Aug 21.

Novel immune biomarkers in complex regional pain syndrome.

Russo M, Georgius P, Staats Pires A, Heng B, Allwright M, Guennewig B, Santarelli D, Bailey D, Fiore NT, Xiuwen Tan V, Latini A, Guillemin GJ, Austin PJ

Journal of Neuroimmunology. 2020; Jul 21.

A Systematic Literature Review of Dorsal Root Ganglion Neurostimulation for the Treatment of Pain.

Deer TR, Hunter CW, Mehta P, Sayed D, Grider JS, Lamer TJ, Pope JE, Falowski S, Provenzano DA, Esposito MF, Slavin KV, Baranidharan G, Russo M, Jassal NS, Mogilner AY, Kapural L, Verrills P, Amirdelfan K, McRoberts WP, Harned ME, Chapman KB, Liem L, Carlson JD, Yang A, Aiyer R, Antony A, Fishman MA, Al-Kaisy AA, Christelis N, Levy RM, Mekhail N.

Pain Medicine. 2020; 21(8): 1581-1589.

A Systematic Literature Review of Spine Neurostimulation Therapies for the Treatment of Pain.

Deer TR, Grider JS, Lamer TJ, Pope JE, Falowski S, Hunter CW, Provenzano DA, Slavin KV, Russo M, Carayannopoulos A, Shah JM, Harned ME, Hagedorn JM, Bolash RB, Arle JE, Kapural L,

Amirdelfan K, Jain S, Liem L, Carlson JD, Malinowski MN, Bendel M, Yang A, Aiyer R, Valimahomed A, Antony A, Craig J, Fishman MA, Al-Kaisy AA, Christelis N, Rosenquist RW, Levy RM, Mekhail N

Pain Medicine. 2020; 21(7): 1421–1432.

10 kHz spinal cord stimulation for chronic upper limb and neck pain: Australian experience.

Verrills P, Salmon J, Russo M, Gliner B, Barnard A, Caraway D

European Spine Journal. 2020; Jun 30.

Weaning Off Opioid Therapy.

Russo M, Santarelli D

In book: Opioid Therapy for Pain: A Practical Guide for Clinicians. 2020.

Sustained Long-Term Outcomes With Closed-Loop Spinal Cord Stimulation: 12-Month Results of the Prospective, Multicenter, Open-Label Avalon Study.

Russo M, Brooker C, Cousins MJ, Taylor N, Boesel T, Sullivan R,Holford L, Hanson E, Gmel GE, Shariati NH, Poree L, Parker J

Neurosurgery. 2020; Feb 05.

2019

The changing face of complex regional pain syndrome treatment.

Russo M, Georgius P, Santarelli D

In book: Australasian Anaesthesia. 2019. Publisher: Australian and New Zealand College of Anaesthetists.

A Novel Composite Metric for Predicting Patient Satisfaction With Spinal Cord Stimulation.

Russo M, Verrills P, Santarelli D, Gupta S, Martin J, Hershey B

Neuromodulation. 2019; 23(5): 687-697.

Leptin and Associated Mediators of Immunometabolic Signaling: Novel Molecular Outcome Measures for Neurostimulation to Treat Chronic Pain.

Kinfe TM, Buchfelder M, Chaudhry SR, Chakravarthy KV, Deer TR, Russo M, Georgius P, Hurlemann R, Rasheed M, Muhammad S, Yearwood TL

International Journal of Molecular Sciences. 2019; 20(19): 4737.

Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome.

Russo M, Fiore NT, van Vreden C, Bailey D, Santarelli DM, McGuire HM, Fazekas de St Groth B, Austin PJ

Journal of Neuroinflammation. 2019; 16(1): 63.

2018

A new hypothesis for the pathophysiology of complex regional pain syndrome.

Russo M, Georgius P, Santarelli DM

Medical Hypotheses. 2018; 119: 41-53.

Cervical spinal cord stimulation for the treatment of essential tremor.

Russo M, Santarelli DM, Smith U

BMJ Case Reports. 2018.

Meaningful relief with flurbiprofen 8.75 mg spray in patients with sore throat due to upper respiratory tract infection.

de Looze F, Russo M, Bloch M, Montgomery B, Shephard A, DeVito R

Pain Management. 2018; 8(2): 79-83.

Muscle Control and Non-specific Chronic Low Back Pain.

Russo M, Deckers K, Eldabe S, Kiesel K, Gilligan C, Vieceli J, Crosby P

Neuromodulation. 2018; 21(1): 1-9 (Editor’s Choice).

Effective Relief of Pain and Associated Symptoms With Closed-Loop Spinal Cord Stimulation System: Preliminary Results of the Avalon Study. Russo M, Cousins MJ, Brooker C, Taylor N, Boesel T, Sullivan R, Poree L, Shariati NH, Hanson E, Parker J

Neuromodulation. 2018; 21(1): 38-47.

New Therapy for Refractory Chronic Mechanical Low Back Pain—Restorative Neurostimulation to Activate the Lumbar Multifidus: One Year Results of a Prospective Multicenter Clinical Trial.

Deckers K, De Smedt K, Mitchell B, Vivian D, Russo M, Georgius P, Green M, Vieceli J, Eldabe S, Gulve A, van Buyten JP, Smet I, Mehta V, Ramaswamy S, Baranidharan G, Sullivan R, Gassin R, Rathmell J, Gilligan C

Neuromodulation. 2018; 21(1): 48-55.

2017

The physiological effects of slow breathing in the healthy human.

Russo M, Santarelli DM, O'Rourke D

Breathe. 2017; 13(4): 298-309.

Pain relief of sore throat with a new anti-inflammatory throat lozenge, ibuprofen 25 mg: A randomised, double-blind, placebo-controlled, international phase III study.

Bouroubi A, Donazzolo Y, Donath F, Eccles R, Russo M, Harambillet N, Gautier S, Montagne A International Journal of Clinical Practice. 2017; 71(9): e12961.

Comment on “Probable Tapentadol-Associated Serotonin Syndrome after Overdose”.

Russo M, Santarelli D, Isbister G

Hospital Pharmacy. 2017; 52(4).

Targeting the cause, not just the symptoms: A new treatment for chronic low back pain – results of the ReActiv8-A trial.

Mitchell B, Deckers K, DeSmedt K, Vivian D, Russo M, Sam E, Gulve A, Harland N, Georgius P, Van Buyten JP, Smet I, Green M, Vieceli J, Baranidharan G, Mehta V, Ramaswamy S, Sullivan R, Gassin R, Rathmell J, Gilligan C

Journal of Science and Medicine in Sport. 2017; 20(S1): e15.

The Neurostimulation Appropriateness Consensus Committee (NACC) Recommendations for Infection Prevention and Management.

Deer TR, Provenzano DA, Hanes M, Pope JE, Thomson SJ, Russo MA, McJunkin T, Saulino M, Raso LJ, Lad SP, Narouze S, Falowski SM, Levy RM, Baranidharan G, Golovac S, Demesmin D, Witt WO, Simpson B, Krames E, Mekhail N

Neuromodulation. 2017; 20(1): 31-50.

The Neurostimulation Appropriateness Consensus Committee (NACC): Recommendations on Bleeding and Coagulation Management in Neurostimulation Devices.

Deer TR, Narouze S, Provenzano DA, Pope JE, Falowski SM, Russo MA, Benzon H, Slavin K, Pilitsis JG, Alo K10, Carlson JD, McRoberts P, Lad SP, Arle J, Levy RM, Simpson B, Mekhail N

Neuromodulation. 2017; 20(1): 51-62.

The Polyanalgesic Consensus Conference (PACC): Recommendations for Trialling of Intrathecal Drug Delivery Infusion Therapy.

Deer TR, Hayek SM, Pope JE, Lamer TJ, Hamza M, Grider JS, Rosen SM, Narouze S, Perruchoud C, Thomson S, Russo M, Grigsby E, Doleys DM, Jacobs MS, Saulino M, Christo P, Kim P, Huntoon EM, Krames E, Mekhail N

Neuromodulation. 2017; 20(2): 133-154.

2016

Chronic Abdominal Wall Pain.

Russo M, Volschenk W and Santarelli D

Journal of Clinical Gastroenterology. 2019; 53(3): e129-130.

Effectiveness of PRP in the Treatment of Tendinopathy: Letter to the Editor.

Russo M, Volschenk W and Santarelli D

The American Journal of Sports Medicine. 2016; 44(10): NP52-NP53.

Effectiveness and tolerability of tapentadol sustained release in the Australian setting.

Russo MA and Santarelli DM

Journal of Opioid Management. 2016; 12(3):187-96.

High Frequency Spinal Cord Stimulation at 10 kHz for the Treatment of Chronic Pain: 6-Month Australian Clinical Experience.

Russo M, Verrills P, Mitchell B, Salmon J, Barnard A and Santarelli D

Pain Physician. 2016; 19(4): 267-280.

Efficacy of Flurbiprofen 8.75 mg spray in patients with sore throat due to an upper respiratory tract infection: A randomised controlled trial.

de Looze F, Russo M, Bloch M, Montgomery B, Shephard A, Smith G and Aspley S

The European Journal of General Practice. 2016; 30: 1-8.

Results from the Partnership for Advancement in Neuromodulation Registry: A 24-Month Follow-Up.

Deer T, Skaribas I, McJunkin T, Nelson C, Salmon J, Darnule A, Braswell J, Russo M, Fernando Gomezese O

Neuromodulation. 2016; 19(2): 179-187.

2015

A Novel Compound Analgesic Cream (Ketamine, Pentoxifylline, Clonidine, DMSO) for Complex Regional Pain Syndrome Patients.

Russo MA and Santarelli DM

Pain Practice. 2015; 16(1): E14-20.

Comment on "In vivo and systems biology studies implicate IL-18 as a central mediator in chronic pain" by Vasudeva et al., J. Neuroimmunol. 2015 June; 283:3-49.

Russo MA and Santarelli DM

Journal of Neuroimmunology. 2015; 286: 77-78.

Improved Pain Relief With Burst Spinal Cord Stimulation for Two Weeks in Patients Using Tonic Stimulation: Results From a Small Clinical Study.

Courtney P, Espinet A, Mitchell B, Russo M, Muir A, Verrills P and Davis K

Neuromodulation. 2015; 18(5): 361-366.

(366) Efficacy of flurbiprofen 8.75 mg spray in patients with relatively severe sore throat symptoms.

Russo M, de Looze F, Bloch M, Montgomery B, Smith G, Shephard A, and Aspley S

The Journal of Pain. 2015; 16(4): S67.

Thoracic Spinal Cord Stimulation for Heart Failure as a Restorative Treatment (SCS HEART study): first-in-man experience.

Tse HF, Turner S, Sanders P, Okuyama Y, Fujiu K, Cheung CW, Russo M, Green MD, Yiu KH, Chen P, Shuto C, Lau EO and Siu CW

Heart Rhythm. 2015; 12(3): 588-595.

10-kHz High-Frequency SCS Therapy: A Clinical Summary.

Russo M and Van Buyten JP

Pain Medicine; 16(5): 934-942.

Lack of body positional effects on paresthesias when stimulating the dorsal root ganglion (DRG) in the treatment of chronic pain.

Kramer J, Liem L, Russo M, Smet I, Van Buyten JP and Huygen F

Neuromodulation. 2015; 18(1): 50-57; discussion 57.

One-year outcomes of spinal cord stimulation of the dorsal root ganglion in the treatment of chronic neuropathic pain.

Liem L, Russo M, Huygen FJ, Van Buyten JP, Smet I, Verrills P, Cousins M, Brooker C, Levy R, Deer T and Kramer J

Neuromodulation. 2015; 18(1): 41-48; discussion 48-49.

2014

The appropriate use of neurostimulation of the spinal cord and peripheral nervous system for the treatment of chronic pain and ischemic diseases: the Neuromodulation Appropriateness Consensus Committee.

Deer TR, Mekhail N, Provenzano D, Pope J, Krames E, Leong M, Levy RM, Abejon D, Buchser E, Burton A, Buvanendran A, Candido K, Caraway D, Cousins M, DeJongste M, Diwan S, Eldabe S, Gatzinsky K, Foreman RD, Hayek S, Kim P, Kinfe T, Kloth D, Kumar K, Rizvi S, Lad SP, Liem L, Linderoth B, Mackey S, McDowell G, McRoberts P, Poree L, Prager J, Raso L, Rauck R, Russo M, Simpson B, Slavin K, Staats P, Stanton-Hicks M, Verrills P, Wellington J, Williams K and North R

Neuromodulation. 2014; 17(6): 515-550; discussion 550.

Re: Freeman BJ, Ludbrook GL, Hall S, et al. Randomized, double-blind, placebo-controlled, trial of transforaminal epidural etanercept for the treatment of symptomatic lumbar disc herniation. Spine 2013;38:1986-94.

Russo MA

Spine (Phila Pa 1976). 2014; 39(15): 1262.

International Neuromodulation Society Critical Assessment: Guideline Review of Implantable Neurostimulation Devices.

Deer TR, Thomson S, Pope JE, Russo M, Luscombe F and Levy R

Neuromodulation. 2014; 17(7): 678-685.

Interim Results From the Partnership for Advancement in Neuromodulation Pain Registry.

Deer T, Skaribas I, Nelson C, Tracy J, Meloy S, Darnule A, Salmon J, Pahapill PA, McJunkin T, Sanapati M, Lininger TE, Russo M, Haider N, Kim CH, Tiso RL, Gomezese OF, Braswell J, Espinet A, Daudt D and Washburn SN

Neuromodulation. 2014; 17(7): 656-664.

Stimulation of Dorsal Root Ganglia for the Management of Complex Regional Pain Syndrome: A Prospective Case Series.

Van Buyten JP, Smet I, Liem L, Russo M and Huygen F

Pain Practice. 2014; 15(3): 208-216.

A multicenter, prospective trial to assess the safety and performance of the spinal modulation dorsal root ganglion neurostimulator system in the treatment of chronic pain.

Liem L, Russo M, Huygen FJ, Van Buyten JP, Smet I, Verrills P, Cousins M, Brooker C, Levy R, Deer T and Kramer J

Neuromodulation 2014; 16(5): 471-482; discussion 482.

2013

Flurbiprofen microgranules for relief of sore throat: a randomised, double-blind trial.

Russo M, Bloch M, de Looze F, Morris C and Shephard A

British Journal of General Practice. 2013; 63(607): e149-155.

2009

Patient preference for sustained-release versus standard paracetamol (acetaminophen): a multicentre, randomized, open-label, two-way crossover study in subjects with knee osteoarthritis.

Benson M, Marangou A, Russo MA, Durocher J, Collaku A and Starkey YY

Journal of International Medical Research. 2009; 37(5): 1321-1335.

Re: Complex regional pain syndrome after infliximab infusion.

Russo MA and Dorahy DJ

Journal of Pain and Symptom Management. 2009; 37(3): e9-10.

2008

Chronic Non-Malignant Pain.

Russo MA, Newton-John T and Lo W

Australian Doctor. 2008; 21(March): 25-32.

2007

A clinical snapshot of transdermal buprenorphine in pain management.

Russo MA and Wasiak J

European Journal of Pain Supplements. 2007; 1(1): 74-77.

2006

Anti-hyperalgesia properties of buprenorphine.

Russo MA

Pain. 2006; 122(1-2): 216; author reply 216.

Recovery from bispectral index-guided anaesthesia.

Russo MA

Anaesthesia and Intensive Care. 2006; 34(1): 127; author reply 127.

2005

Letter to the editor regarding Reig et al., Thermocoagulation of the ganglion impar of Walther: description of a modified approach. Preliminary results in chronic, nononcological pain. Pain Practice 2005;5(2):103-110.

Russo MA

Pain Practice. 2005; 5(4): 367.

2004

Inadvertent subdural spread complicating cervical epidural steroid injection - Reply.

Russo MA

Anaesthesia and Intensive Care. 2004; 32(1): 145-146.

1997

Dilutional acidosis: a nonentity?

Russo MA

Anesthesiology. 1997; 87(4): 1010-1011; Author Reply 1013-1014.

Conference Abstracts

2021

10 kHz SCS for Failed Neck Surgery Syndrome: Analysis of Data from Two Multicenter Studies. Kasra Amirdelfan, Ricardo Vallejo, John Salmon, Ramsin Benyamin, Cong Yu, Thomas Yang, Richard Bundschu, Thomas Yearwood, Todd Sitzman, Marc Russo, Adele Barnard, Anand Rotte, Paul Verrills. Presented at: North American Neuromodulation Society 2021 Virtual Meeting.

24-Month Avalon Study Data Indicates Improved Pain Reduction With Decreased Opioid Use.

Nastaran Hesam Shariati, Charles Brooker, Marc Russo, Nathan Taylor, Tillman Boesel, Richard Sullivan, Erin Hanson, Gerrit Gmel, Lawrence Poree, Lewis Holford, John L. Parker. Presented at: North American Neuromodulation Society 2021 Virtual Meeting.

Four Year Treatment Durability and Effectiveness of Restorative Neurostimulation for Intractable Chronic Low Back Pain. Sam Eldabe, Marc Russo, Bruce Mitchell, Matthew Green, Vivek Mehta, Ganesan Barani, Ashish Gulve, Jean Pierre Van Buyten, Kristiaan J. Deckers, Kris De Smedt, Iris Smet, Peter Georgius. Presented at: North American Neuromodulation Society 2021 Virtual Meeting.

Improved Versatility and Frequency Pairing Capabilities with 10 kHz Spinal Cord Stimulation for Chronic Pain. Marc Russo, Frank Thomas, John Prickett, Simon Tame, Richard Pendleton, Daniel Berge, Brett Todhunter, Richard Sullivan, Gavin Weekes, Geoff Speldewinde, James Yu, John Monagle, Michael Bassett, Tillman Boesel, Romil Jain, Tim Ho, Matthew Green, Neels DuToit, Paul Verrills, John Salmon, Brett Chandler, Daniel Bates, Lewis Holford, Nathan Taylor, Adele Barnard. Presented at: North American Neuromodulation Society 2021 Virtual Meeting.

Pain Relief Outcomes Using Neuromodulation Systems with Multiple Waveform and Programming Modalities: An Australian Case-Series. Peter Georgius, Bruce Mitchell, David Holthouse, John Monagle, Thierry Vancaillie, Marc Russo, Jing Wang. Presented at: North American Neuromodulation Society 2021 Virtual Meeting.

2020

Chronic Pain Outcomes Using a Neuromodulation System with Multiple Waveform and Programming Modalities in Australia. Peter Georgius, Marc Russo, John Monagle, Jing Wang, Roshini Jain. Presented at: American Society of Interventional Pain Physicians Annual Meeting, Las Vegas, NV, USA.

Targeting the Dorsal Horn - an Innovative Technique (SUBWAVE) and Early Clinical Trial Results.

Marc Russo, Dominic Bailey, Willem Volschenk, Mazyar Danesh, Danielle Santarelli. Presented at: American Society of Interventional Pain Physicians Annual Meeting, Las Vegas, NV, USA.

Avalon Study: Long-Term Impact of ECAP-Controlled Closed-Loop SCS on Pain, Patient Wellbeing and Clinical Practice.

Marc Russo, Charles Brooker, Richard Sullivan, Nathan Taylor, Lewis Holford, Tillman Boesel, Gerrit Gmel, Nastaran Shariati, Lawrence Poree, John Parker.

Presented at: American Society of Interventional Pain Physicians Annual Meeting, Las Vegas, NV, USA.

Improved Versatility and Frequency Pairing Capabilities with 10kHz SCS for the Treatment of Chronic Pain. Adele Cassar, Marc Russo, Frank Thomas, Simon Tame, John Prickett, Richard Pendleton, Daniel Berge, Christina Keilar, Liam Pritchard, Adele Barnard. Presented at: American Society of Interventional Pain Physicians Annual Meeting, Las Vegas, NV, USA.

10 kHz Spinal Cord Stimulation for Upper Limb and Neck pain: Australian Experience–Quality of Life Outcomes. Adele Cassar, Paul Verrills, John Salmon, Marc Russo. Presented at: American Society of Interventional Pain Physicians Annual Meeting, Las Vegas, NV, USA.

2019

Long-Term Results of ECAP-Controlled Closed-Loop SCS.

Jason Pope, Marc Russo, on behalf of the Avalon Study Investigators.

Presented at: American Society of Interventional Pain Physicians Annual Meeting, Las Vegas, NV, USA.

Automated, Routine Monitoring of Neurophysiological Parameters in Spinal Cord Stimulation.

Nathan Taylor, Marc Russo, Abeer Khurram, Robert Gorman.

Presented at: 7th Minnesota Neuromodulation Symposium, Minneapolis, MN, USA.

A Prospective Global Registry of Real-World Outcomes Using Spinal Cord Stimulation Systems for Chronic Pain.

Richard Rauck, Simon Thomson, RELIEF Study Group, Rex Woon, Kristen Lechleiter, Roshini Jain.

Presented at: North American Neuromodulation Society 22nd Annual Meeting, Las Vegas, NV, USA.

Spinal Cord Stimulation Failures: Underlying Mechanisms and Clinical Outcomes.

Peter Staats, Marc Russo, Charles Brooker, Jason Pope, Milan Obradovic, John L Parker.

Presented at: North American Neuromodulation Society 22nd Annual Meeting, Las Vegas, NV, USA.

Neural Response Profile: Objective Neurophysiological Measurements and Pain Relief in Spinal Cord Stimulation.

Marc Russo, Charles Brooker, Nathan Taylor, Brian Hills, Abeer Khurram, John L Parker.

Presented at: North American Neuromodulation Society 22nd Annual Meeting, Las Vegas, NV, USA.

Effective Relief of Pain and Associated Symptoms with Closed-Loop Spinal Cord Stimulation System: Long-Term Results.

Charles Brooker, Marc Russo, Lawrence Poree, Michael J Cousins, Richard Sullivan, Nathan Taylor, Lewis Holford, Tillman Boesel, Rebecca Martin, Martine O’Beill, Erin Hanson, Nastaran Hesam Shariati, John L Parker.

Presented at: North American Neuromodulation Society 22nd Annual Meeting, Las Vegas, NV, USA.

Effective Relief of Pain and Associated Symptoms with Closed-Loop Spinal Cord Stimulation System: 18-Month Results. Marc Russo, Charles Brooker, Lawrence Poree, Michael J. Cousins, Richard Sullivan, Nathan Taylor, Lewis Holford, Tillman Boesel, Rebecca Martin, Martine O’Neill, Erin Hanson, Nastaran Hesam Shariati, John L. Parker.

Presented at: International Neuromodulation Society 14th World Congress, Sydney, NSW, Australia.

2018

Automated, routine monitoring of neurophysiological parameters in spinal cord stimulation.

Presented at: American Society of Regional Anaesthesia and Pain Medicine 17th Annual Pain Medicine Meeting, San Antonio, TX, USA | California Society of Interventional Pain Physicians 9th Annual Meeting, Santa Barbara, CA, USA | New York & New Jersey Societies of Interventional Pain Physicians Annual Meeting, Jersey City, NJ, USA.

Neural response profile: objective neurophysiological measurement of pain relief in spinal cord stimulation.

Presented at: California Society of Interventional Pain Physicians 9th Annual Meeting, Santa Barbara, CA, USA | New York & New Jersey Societies of Interventional Pain Physicians Annual Meeting, Jersey City, NJ, USA.

Effective relief of pain and associated symptoms with closed-loop spinal cord stimulation system: 12-month results.

Charles Brooker, Marc Russo, Lawrence Poree, Michael J Cousins, Richard Sullivan, Nathan Taylor, Lewis Holford, Tillman Boesel, Rebecca Martin, Martine O’Neill, Erin Hanson, Nastaran Hesam Shariati, John L Parker.

Long-Term Results from the Avalon Study - Closed-Loop SCS using Evoked Compound Action Potentials.

Marc Russo, Timothy Deer, Lawrence Poree, Michael J Cousins, Charles Brooker, Richard Sullivan, Tillman Boesel, Nathan Taylor, Rebecca Martin, Martine O’Niell, John L Parker.

Presented at: North American Neuromodulation Society 21st Annual Meeting, Las Vegas, NV, USA.

A Multi-Center, Prospective, Clinical Trial of High Frequency Spinal Cord Stimulation (HF-SCS) at 10 kHz in the Treatment of Chronic Upper Limb and Neck Pain.

Paul Verrills, John Salmon, Marc Russo.

Presented at: North American Neuromodulation Society 21st Annual Meeting, Las Vegas, NV, USA.

An investigation into the therapeutic effect of electrical impulses with short pulse (SP) width on pain relief and quality of the spinal cord stimulation (SCS) in patients with intractable back and / or leg pain.

Charles Brooker, Marc Russo, Michael J Cousins, Richard Sullivan, Tillman Boesel, Nathan Taylor, Rebecca Martin, Martine O’Neill, Lawrence Poree, Erin Hanson, John L Parker

Presented at: North American Neuromodulation Society 21st Annual Meeting, Las Vegas, NV, USA.

2017

Electrophysiological Insight into Dorsal Column Neuroanatomy and the Mechanism of Action of Spinal Cord Stimulation (SCS).

Marc Russo, Robert Levy, John Parker.

Poster presented at: North American Neuromodulation Society 20th Annual Meeting, Las Vegas, NV, USA.

Restorative Neurostimulation for Refractory Chronic Low Back Pain: Two-Year Results from the Reactiv8-A Clinical Trial.

Kristiaan J. Deckers, Kris L. De Smedt, Bruce Mitchell, David G. Vivian, Marc A. Russo, Peter Georgius, Matthew D. Green, John Vieceli, Sam Eldabe, Ashish Gulve, Jean-Pierre van Buyten, Iris Smet, Vivek Mehta, Shankar Ramaswamy, Ganesan Baranidharan, Richard Sullivan, Robert Gassin, James P. Rathmell, Christopher J. Gilligan.

Poster presented at: North American Spine Society 32nd Annual Meeting, Orlando, FL, USA.

A Review of Treatments for Chronic Complex Regional Pain Syndrome.

Marc Russo and Danielle Santarelli.

Poster presented at: International Neuromodulation Society 13th World Congress, Edinburgh, Scotland.

A Case Series Examination of Recovered Long-Term Pain Relief Utilizing a Multiple Waveform Neurostimulator in Patients Who Experienced a Loss of Treatment Efficacy Using Spinal Cord Stimulation.

Nick Christelis, John Monagle, Marc Russo.

Poster presented at: International Neuromodulation Society 13th World Congress, Edinburgh, Scotland.

Real-World Retrospective Audit of Long-Term Clinical Outcomes Beyond 24 Months in Chronic Pain Patients Using a Multiple Waveform Neurostimulation System in Australia.

John Monagle, Marc Russo, Nick Christelis.

Poster presented at: International Neuromodulation Society 13th World Congress, Edinburgh, Scotland.

Treating the Wide Range of Chronic Intractable Pain Conditions Using a Multiple Waveform-Based Neurostimulator System in Australia: a Real World, Clinical Audit.

Marc Russo, Nick Christelis, John Monagle.

Poster presented at: International Neuromodulation Society 13th World Congress, Edinburgh, Scotland.

Use of Peripheral Nerve Stimulation And Spinal Cord Stimulation to Treat Chronic Pain Patients in Australia.

Peter Georgius, Marc Russo, John Monagle, Nick Christelis.

Poster presented at: International Neuromodulation Society 13th World Congress, Edinburgh, Scotland.

2016

Rationale for Specificity of Anatomic Target of HF10 Stimulation.

Marc Russo.

Poster presented at: Neuromodulation Society of Australia and New Zealand 11th Annual Scientific Meeting, Perth, WA, Australia.

2015

An Audit of Early Tapentadol Use in the Australian Setting.

Marc Russo, Julia Busquets and Danielle Santarelli.

Poster presented at: Australian Pain Society 35th Annual Scientific Meeting, Brisbane, QLD, Australia.

Rescuing HF10 Therapy – A Case Study.

Marc Russo

Poster presented at: International Neuromodulation Society 12th World Congress, Montreal, Canada.

High Frequency Spinal Cord Stimulation at 10 kHz for Complex Regional Pain Syndrome.

Marc Russo, Dominic Bailey, Danielle Santarelli.

Poster presented at: North American Neuromodulation Society 19th Annual Meeting, Las Vegas, NV, USA.

Cervical Spinal Cord Stimulation in the Treatment of Essential Tremor: A Case Report.

Marc Russo, Ushtana Smith, Danielle Santarelli

Poster presented at: North American Neuromodulation Society 19th Annual Meeting, Las Vegas, NV, USA.

2014

High Frequency Spinal Cord Stimulation at 10 kHz for the Treatment of Chronic Pain: 6 Month Real World Effectiveness.

Marc Russo, Paul Verrills, Bruce Mitchell, John Salmon, Adele Barnard and Danielle Santarelli.

Presented at: North American Neuromodulation Society 18th Annual Meeting, Las Vegas, NV, USA.

Significant Pain Relief with Subperception SCS (SubPSCS) at Standard Stimulation Rates: Exploratory research of SubPSCS at ≤1.2kHz.

Paul Verrills, Marc Russo, Sherry Lin, Brad Hershey.

Poster presented at: North American Neuromodulation Society 18th Annual Meeting, Las Vegas, NV, USA.

Dual-targeted Thoracic Spinal Cord Stimulation for Heart Failure as a Restorative Treatment (SCS HEART Study): First-in-man Experience.

Hung‐Fat Tse, Stuart Turner, Prashanthan Sanders, Yuji Okuyama,Katsuhito Fujiu, Chi‐Wai Cheung, Marc Russo, Matthew D.S.Green, Kai‐Hang Yiu, Elizabeth O.Y. Lau, Chung‐Wah Siu

Presented at: Heart Rhythm Society 35th Annual Scientific Sessions, San Francisco, CA, USA.

Real World Outcomes of a Novel Compound Analgesic Cream (Ketamine, Pentoxifylline, Clonidine and DMSO) for CRPS.

Marc Russo and Danielle Santarelli.

Poster presented at: IASP 15th World Congress on Pain, Buenos Aires, Argentina.

High Frequency Spinal Cord Stimulation for the Treatment of Chronic Pain: 12 Month Real-World Effectiveness.

Marc Russo, Paul Verrills, Bruce Mitchell, John Salmon, Thomas Berrigan, Adele Barnard, Danielle Santarelli.

Poster presented at: Neuromodulation Society of Australia and New Zealand 9th Annual Scientific Meeting, Hobart, Tasmania, Australia.

Cluneal Nerve Stimulation for Refractory Low Back Pain.

Marc Russo and Danielle Santarelli.

Poster presented at: Neuromodulation Society of Australia and New Zealand 9th Annual Scientific Meeting, Hobart, Tasmania, Australia.

Contact

To get in touch with Dr. Russo, please fill in the form below.